Endocrine Abstracts

Polycystic Ovary Syndrome increases the risk of cardiovascular diseases. To factors predisposing to cardiovascular diseases belong: hypertension, lipid and carbohydrate profiles, smoking and reduced physical activity. The aim of this study was to determine the association between selected factors predisposing to cardiovascular diseases and anthropometric parameters and CRP concentration in women with Polycystic Ovary Syndrome. The study was conducted amongst 43 women, aged 18-...

Introduction: Hypopituitarism can be caused by a number of different etiologic factors including metastatic cancer. Metastasis to the pituitary gland is rare, accounting for only 1.8% of all metastases, and is often detected incidentally by symptoms associated with hormone dysfunction like hyponatremia. Breast and lung cancer are the primary neoplasms with well established properties of pituitary infiltration. Metastases from gastric cancer are unusual and constitute less than...

Introduction: Adrenal insufficiency is a rare cause of life-threatening hyponatraemic collapse in the neonatal period. The initial investigations taken at the time of presentation, and prior to the institution of hydrocortisone, are a key step in the diagnostic pathway.Aim: We present a case series where the initial biochemical test results could have led to a delay in diagnosis or early discontinuation of hydrocortisone.Ca...

Background: Nutritional rickets (NR), due to poor dietary calcium intake or vitamin D deficiency is still the most common form of growing bone disease despite the efforts of health care providers to reduce its incidence. Clinical history, physical examination and laboratory evaluation are mainstay of diagnosis.Aim: We report a case of NR where the radiological report was misleading causing significant parental anxiety and delay in diagnosis.<p class=...

Introduction: Adrenal cancer is a rare, highly invasive malignant tumour with the incidence estimated for approximately 0,5-2,0 cases per milion people annually. Considering the fact that adrenal cancer is very sporadic not much data on its epidemiology is available.Aim of the study: The aim of the study was to present the single-center data on the epidemiology of the adrenal cancer.Material and methods: Patients with the diagnosis...

Primary thyroid lymphoma (PTL) is a rare disorder, representing merely 1-5% of all thyroid malignancies, 1-2% of extranodal lymphomas and 3% of non-Hodgkin’s lymphomas. It affects mainly women. PTL incidence is low in individuals younger than 40 years old. The most common clinical presentation of PTL is a palpable mass in the neck. It may be accompanied by other symptoms: dysphagia, dyspnea, and hoarseness. Diffuse B-cell lymphoma (DLBCL), is the most common pathological ...

Iodine deficiency is considered the most common preventable cause of brain damage worldwide. It is particularly important during pregnancy, as it influences not only mothers but their fetuses as well. The Polish model of iodine prophylaxis is based on obligatory household salt iodization and recommendation of iodine-containing supplements for pregnant women. The aim of the study was to assess the current iodine status of pregnant women and to compare it with earlier results.</...

Somatic cells of the seminiferous epithelium, called Sertoli cells, play a key role in germ cell development and maintenance of proper course of spermatogenesis. Although androgens are considered the main regulators of Sertoli cell activity, recent studies indicate that their metabolites, estrogens, also influence Sertoli cell function. Estrogens, act mainly through nuclear estrogen receptors α and β (ERα, ERβ), however non-classical signaling via ...

Introduction: It is well known that DHEA and DHEA-S has and impact on lipid metabolism, cardiovascular system and others. De Castro et al. showed that cortisol/DHEA-S ratio was an independent predictor of long-term mortality in patients with sepsis. Chronic inflammation is an important factor in cardiovascular diseases development that reduce quality and life expectancy. CVDs are more common in patients with adrenal incidentaloma than in general population. Literature data on ...

Background: Growth monitoring identifies treatable conditions in apparently healthy children and prevents inappropriate referrals. Systematic growth monitoring is not currently a UK priority and growth disorders are frequently diagnosed late.Objectives: Develop and test the accuracy of a smartphone app which enables families to measure a child’s height at home as a cost-effective alternative to primary care growth monitoring.M...